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Literature summary for 4.1.3.27 extracted from

  • Zalkin, H.
    Anthranilate synthase (1985), Methods Enzymol., 113, 287-292.
    View publication on PubMed
Search for more literature for 4.1.3.27

Inhibitors

Inhibitors Comment Organism Structure
L-Trp
-
 Serratia marcescens

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.004
-
 chorismate
-
 Serratia marcescens
0.5
-
 Gln
-
 Serratia marcescens
5.9
-
 NH4+
-
 Serratia marcescens

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
20956
-
 2 * 20956 + 2 * 60000 Serratia marcescens
60000
-
 2 * 20956 + 2 * 60000 Serratia marcescens

Organism

Organism UniProt Comment Textmining
Serratia marcescens
-
-
-
Serratia marcescens HY150
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Serratia marcescens

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Serratia marcescens

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
chorismate + L-Gln
-
 Serratia marcescens anthranilate + pyruvate + L-glutamate
-
 ?
chorismate + L-Gln
-
 Serratia marcescens HY150 anthranilate + pyruvate + L-glutamate
-
 ?
chorismate + NH4+
-
 Serratia marcescens ?
-
 ?
chorismate + NH4+
-
 Serratia marcescens HY150 ?
-
 ?

Subunits

Subunits Comment Organism
More subunit ASI catalyzes NH4+-dependent synthesis of anthranilate. Gln is not a substrate for ASI. ASII provides Gln-amide transfer function Serratia marcescens
tetramer 2 * 20956 + 2 * 60000 Serratia marcescens

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
-
 Serratia marcescens
8.5
-
-
 Serratia marcescens