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Literature summary for 4.1.3.22 extracted from
- Citramalate pyruvate lyase (1969), Methods Enzymol., 13, 344-346.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Ca2+ | 1 mM | Clostridium tetanomorphum |  |
| diphosphate | - |
Clostridium tetanomorphum | |
| EDTA | - |
Clostridium tetanomorphum | |
| Fe2+ | 1 mM | Clostridium tetanomorphum | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.6 | - |
(+)-citramalate | - |
Clostridium tetanomorphum | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Co2+ | Mn2+, Mg2+ or Co2+ required | Clostridium tetanomorphum | |
| Mg2+ | or an equivalent divalent cation is required | Clostridium tetanomorphum | |
| Mg2+ | Km for MgCl2: 0.1 mM | Clostridium tetanomorphum | |
| Mn2+ | Mn2+, Mg2+ or Co2+ required | Clostridium tetanomorphum | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Clostridium tetanomorphum | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| acetate + pyruvate | - |
Clostridium tetanomorphum | (+)-citramalate | - |
? | |
| citramalate | - |
Clostridium tetanomorphum | acetate + pyruvate | - |
? | |
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Release 2023.1 (January 2023)
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