Inhibitors | Comment | Organism | Structure |
---|---|---|---|
NaBH4 | azomethine formation with substrates and substrate analogues | Bos taurus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
additional information | no requirement | Bos taurus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | - |
bovine | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
liver | - |
Bos taurus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-Hydroxy-2-oxoglutarate | both stereoisomers | Bos taurus | Pyruvate + glyoxylate | - |
? | |
Glyoxylate + pyruvate | higher specificity for pyruvate than for glyoxylate | Bos taurus | 4-Hydroxy-2-ketoglutarate | - |
? | |
additional information | mechanism | Bos taurus | ? | - |
? | |
additional information | 2-keto-4-hydroxy-4-methylglutarate, 2-keto-3-deoxy-6-phosphoclucanate cleaved at slow rate | Bos taurus | ? | - |
? | |
additional information | acts on both stereoisomers | Bos taurus | ? | - |
? | |
additional information | 2-keto-3-deoxyglucarate and 2-keto-4,5-dihydroxyvalerate cleaved at slow rate | Bos taurus | ? | - |
? | |
Oxaloacetate | beta-decarboxylation, about 50% as effective as aldolase | Bos taurus | CO2 + pyruvate | - |
? |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
13.5 | - |
DL-2-keto-4-hydroxyglutarate | - |
Bos taurus |