Literature summary for 4.1.2.56 extracted from

Suzuki, H.; Ohnishi, Y.; Furusho, Y.; Sakuda, S.; Horinouchi, S.
Novel benzene ring biosynthesis from C3 and C4 primary metabolites by two enzymes (2006), J. Biol. Chem., 281, 36944-36951.

Search for more literature for 4.1.2.56

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Streptomyces griseus

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0056	-	L-aspartate 4-semialdehyde	pH 7.2, 30°C	Streptomyces griseus
0.14	-	glycerone phosphate	pH 7.2, 30°C	Streptomyces griseus

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
30000	-	gel filtration	Streptomyces griseus
33000	-	10 * 33000, SDS-PAGE	Streptomyces griseus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
glycerone phosphate + L-aspartate 4-semialdehyde	Streptomyces griseus	-	2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate	-	?
glycerone phosphate + L-aspartate 4-semialdehyde	Streptomyces griseus TK21	-	2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces griseus	A0JC77	-	-
Streptomyces griseus TK21	A0JC77	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Streptomyces griseus

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
glycerone phosphate + L-aspartate 4-semialdehyde	-	Streptomyces griseus	2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate	-	?
glycerone phosphate + L-aspartate 4-semialdehyde	part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus	Streptomyces griseus	2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate	-	?
glycerone phosphate + L-aspartate 4-semialdehyde	-	Streptomyces griseus TK21	2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate	-	?
glycerone phosphate + L-aspartate 4-semialdehyde	part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus	Streptomyces griseus TK21	2-amino-4,5-dihydroxy-6-oxo-7-(phosphooxy)heptanoate	-	?

Subunits

Subunits	Comment	Organism
decamer	10 * 33000, SDS-PAGE	Streptomyces griseus

Synonyms

Synonyms	Comment	Organism
griI	-	Streptomyces griseus

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
30	-	assay at	Streptomyces griseus

Temperature Stability [°C]

Temperature Stability Minimum [°C]	Temperature Stability Maximum [°C]	Comment	Organism
40	-	stable below	Streptomyces griseus

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.2	-	glycerone phosphate	pH 7.2, 30°C	Streptomyces griseus
0.2	-	L-aspartate 4-semialdehyde	pH 7.2, 30°C	Streptomyces griseus

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
8	-	-	Streptomyces griseus

pH Stability

pH Stability	pH Stability Maximum	Comment	Organism
6.5	10	1 h, 30°C, stable	Streptomyces griseus

General Information

General Information	Comment	Organism
physiological function	part of the pathway for the biosynthesis of grixazone, a mixture of yellow pigments produced by the bacterium Streptomyces griseus	Streptomyces griseus

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Release 2023.1 (January 2023)