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Literature summary for 4.1.2.47 extracted from
- A high-throughput screening assay for hydroxynitrile lyase activity (2006), Chem. Commun. (Camb. ), 28, 4201-4203.
Application
| Application | Comment | Organism |
|---|---|---|
| analysis | cyanide-based high-throughput screening assay is developed. The assay is useful to detect activity and enantioselectivity of hydroxynitrile lyases theoretically towards any cyanohydrin substrate | Manihot esculenta |
| synthesis | the enzyme is a valuable catalysts for the synthesis of cyanohydrins, which are versatile chiral building blocks in the pharmaceutical and agrochemical industries | Manihot esculenta |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Manihot esculenta | P52705 | - |
- |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| additional information | - |
cyanide-based high-throughput screening assay is developed. The assay is useful to detect activity and enantioselectivity of hydroxynitrile lyases theoretically towards any cyanohydrin substrate | Manihot esculenta |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (S)-mandelonitrile | high selectivity towards the (S)-enentiomer | Manihot esculenta | cyanide + benzaldehyde | - |
? |  |
| 2-hydroxy-2-methylpropanenitrile | - |
Manihot esculenta | cyanide + acetone | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MeHNKL | - |
Manihot esculenta |
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