Literature summary for 4.1.2.47 extracted from

Siritunga, D.; Arias-Garzon, D.; White, W.; Sayre, R.T.
Over-expression of hydroxynitrile lyase in transgenic cassava roots accelerates cyanogenesis and food detoxification (2004), Plant Biotechnol. J., 2, 37-43.

Cloned(Commentary)

Cloned (Comment)	Organism
overexpression of the enzyme in transgenic Manihot esculenta plants under the control of a double 35S CaMV promoter. Enzyme activity increases more than 2fold in leaves 13fold in roots of transgenic plants relative to wild-type plants. Elevated levels of hydroxynitrile lyase levels are correlated with substantially reduced acetone cyanohydrin levels and increased cyanide volatilization in processed or homogenized roots. Unlike acyanogenic cassava, transgenic plants overexpressing the enzyme in root retain herbivore deterrence of cyanogens while providing a safer food product (cyanide toxicity)	Manihot esculenta

Cloned (Comment)

Organism

overexpression of the enzyme in transgenic Manihot esculenta plants under the control of a double 35S CaMV promoter. Enzyme activity increases more than 2fold in leaves 13fold in roots of transgenic plants relative to wild-type plants. Elevated levels of hydroxynitrile lyase levels are correlated with substantially reduced acetone cyanohydrin levels and increased cyanide volatilization in processed or homogenized roots. Unlike acyanogenic cassava, transgenic plants overexpressing the enzyme in root retain herbivore deterrence of cyanogens while providing a safer food product (cyanide toxicity)

Manihot esculenta

Organism

Organism	UniProt	Comment	Textmining
Manihot esculenta	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
root	low expression	Manihot esculenta	-

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Release 2023.1 (January 2023)