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Literature summary for 4.1.2.47 extracted from
- Hydroxynitrile lyases in stereoselective catalysis (2000), Curr. Opin. Biotechnol., 11, 532-539.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| succesfully overexpressed in Escherichia coli, Saccharomyces cerevisiae and Pichia pastoris | Manihot esculenta |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 42000 | - |
2 * 42000 | Linum usitatissimum |
| 82000 | - |
- |
Linum usitatissimum |
| 92000 | 124000 | - |
Manihot esculenta |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Acetone cyanhydrin | Manihot esculenta | - |
Cyanide + acetone | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Linum usitatissimum | - |
flax | - |
| Manihot esculenta | - |
maniot | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Acetone cyanhydrin | - |
Manihot esculenta | Cyanide + acetone | - |
? | |
| HCN + (E)-2-butenal | - |
Manihot esculenta | (3E)-2-hydroxypent-3-enenitrile | - |
? | |
| HCN + 2,2-dimethylpropanal | - |
Manihot esculenta | 2-hydroxy-3,3-dimethylbutyronitrile | - |
? | |
| HCN + 2-chlorobenzaldehyde | - |
Manihot esculenta | (2-chlorophenyl)(hydroxy)acetonitrile | - |
? | |
| HCN + 2-hexenal | - |
Manihot esculenta | 2-hydroxyhept-3-enenitrile | - |
? | |
| HCN + 2-propenal | - |
Manihot esculenta | 2-hydroxybut-3-enenitrile | - |
? | |
| HCN + 3-furylcarbaldehyde | - |
Manihot esculenta | hydroxy(fur-3yl)acetonitrile | - |
? | |
| HCN + 4-methoxybenzaldehyde | - |
Manihot esculenta | (4-methoxyphenyl) (hydroxy)acetonitrile | - |
? | |
| HCN + benzaldehyde | - |
Linum usitatissimum | (R)-mandelonitrile | - |
? | |
| HCN + benzaldehyde | - |
Manihot esculenta | (R)-mandelonitrile | - |
? | |
| HCN + benzene-1,2,4-tricarbaldehyde | - |
Manihot esculenta | ? | - |
? | |
| HCN + isobutyraldehyde | - |
Manihot esculenta | 2-hydroxy-3-methylbutyronitrile | - |
? | |
| HCN + pentanal | - |
Manihot esculenta | 2-hydroxyhexanenitrile | - |
? | |
| HCN + propanal | - |
Manihot esculenta | 2-hydroxybutanenitrile | - |
? | |
| HCN + thiophen-2-carbaldehyde | - |
Manihot esculenta | hydroxy(thien-2-yl)acetonitrile | - |
? | |
| HCN + thiophen-3-carbaldehyde | - |
Manihot esculenta | hydroxy(thien-3-yl)acetonitrile | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| dimer | 2 * 42000 | Linum usitatissimum |
| polymer | x * 28000-30000 | Manihot esculenta |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| (R)-LuHNL | - |
Linum usitatissimum |
| (R)-Oxynitrilase | - |
Linum usitatissimum |
| (S)-HNL | - |
Manihot esculenta |
| (S)-MeHNL | - |
Manihot esculenta |
| HNL | - |
Linum usitatissimum |
| HNL | - |
Manihot esculenta |
| Hydroxynitrile lyase | - |
Linum usitatissimum |
| Hydroxynitrile lyase | - |
Manihot esculenta |
| LuHNL | - |
Linum usitatissimum |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 5.4 | - |
- |
Manihot esculenta |
| 5.5 | - |
- |
Linum usitatissimum |
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Release 2023.1 (January 2023)
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