Literature summary for 4.1.2.46 extracted from

Trummler, K.; Wajant, H.
Molecular cloning of acetone cyanohydrin lyase from flax (Linum usitatissimum). Definition of a novel class of hydroxynitrile lyases (1997), J. Biol. Chem., 272, 4770-4774.

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Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Linum usitatissimum

Inhibitors

Inhibitors	Comment	Organism	Structure
diisopropyl fluorophosphate	10 mM, 25% inhibition	Linum usitatissimum

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
45780	-	x * 45780, calculated from sequence	Linum usitatissimum

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
2-hydroxy-2-methylpropanenitrile	Linum usitatissimum	the enzyme is involved in the catabolism of cyanogenic glycosides in young seedlings of Linum usitatissimum	cyanide + acetone	-	?

Organism

Organism	UniProt	Comment	Textmining
Linum usitatissimum	P93243	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-hydroxy-2-methylpropanenitrile	the enzyme is involved in the catabolism of cyanogenic glycosides in young seedlings of Linum usitatissimum	Linum usitatissimum	cyanide + acetone	-	?

Subunits

Subunits	Comment	Organism
?	x * 45780, calculated from sequence	Linum usitatissimum

Synonyms

Synonyms	Comment	Organism
Acetone cyanohydrin lyase	-	Linum usitatissimum
Hydroxynitrile lyase	-	Linum usitatissimum
LuHNL	-	Linum usitatissimum

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Release 2023.1 (January 2023)