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Literature summary for 4.1.2.43 extracted from
- The physiological role of the ribulose monophosphate pathway in bacteria and archaea (2006), Biosci. Biotechnol. Biochem., 70, 10-21.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Pyrococcus horikoshii |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.059 | - |
D-ribulose 5-phosphate | - |
Methylomonas aminofaciens |  |
| 0.083 | - |
D-ribulose 5-phosphate | - |
Methylococcus capsulatus | |
| 0.136 | - |
D-ribulose 5-phosphate | - |
Methylophilus methylotrophus | |
| 0.15 | - |
formaldehyde | - |
Bacillus sp. (in: Bacteria) | |
| 0.29 | - |
formaldehyde | - |
Methylomonas aminofaciens | |
| 0.45 | - |
D-ribulose 5-phosphate | - |
Bacillus sp. (in: Bacteria) | |
| 0.49 | - |
formaldehyde | - |
Methylococcus capsulatus | |
| 0.53 | - |
formaldehyde | - |
Methylophilus methylotrophus | |
| 1.1 | - |
formaldehyde | - |
Methylomonas sp. | |
| 1.5 | - |
formaldehyde | - |
Mycobacterium gastri | |
| 1.6 | - |
D-ribulose 5-phosphate | - |
Methylomonas sp. | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | dependent on | Methanosarcina barkeri | |
| Mg2+ | dependent on | Bacillus sp. (in: Bacteria) | |
| Mg2+ | dependent on | Methylophilus methylotrophus | |
| Mg2+ | dependent on | Pyrococcus horikoshii | |
| Mg2+ | dependent on | Methanosarcina mazei | |
| Mg2+ | dependent on | Methylomonas sp. | |
| Mg2+ | dependent on | Mycobacterium gastri | |
| Mg2+ | dependent on | Methylomonas aminofaciens | |
| Mg2+ | dependent on | Methylococcus capsulatus | |
| Mn2+ | dependent on | Methanosarcina barkeri | |
| Mn2+ | dependent on | Bacillus sp. (in: Bacteria) | |
| Mn2+ | dependent on | Methylophilus methylotrophus | |
| Mn2+ | dependent on | Pyrococcus horikoshii | |
| Mn2+ | dependent on | Methanosarcina mazei | |
| Mn2+ | dependent on | Methylomonas sp. | |
| Mn2+ | dependent on | Mycobacterium gastri | |
| Mn2+ | dependent on | Methylomonas aminofaciens | |
| Mn2+ | dependent on | Methylococcus capsulatus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 22000 | - |
2 * 22000 | Methylomonas sp. |
| 22500 | - |
2 * 22500 | Methylophilus methylotrophus |
| 23000 | - |
2 * 23000 | Methylomonas aminofaciens |
| 24000 | - |
2 * 24000 | Mycobacterium gastri |
| 27000 | - |
2 * 27000 | Bacillus sp. (in: Bacteria) |
| 32000 | - |
holenzyme | Bacillus sp. (in: Bacteria) |
| 40000 | - |
holenzyme | Methylophilus methylotrophus |
| 43000 | - |
holenzyme | Mycobacterium gastri |
| 44000 | - |
holenzyme | Methylomonas sp. |
| 46000 | - |
holoenzyme | Methylomonas aminofaciens |
| 49000 | - |
6 * 49000 | Methylococcus capsulatus |
| 310000 | - |
holoenzyme | Methylococcus capsulatus |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bacillus sp. (in: Bacteria) | - |
- |
- |
| Bacillus sp. (in: Bacteria) C1 | - |
- |
- |
| Methanosarcina barkeri | - |
- |
- |
| Methanosarcina mazei | - |
- |
- |
| Methylococcus capsulatus | Q602L4 | - |
- |
| Methylomonas aminofaciens | Q48907 | - |
- |
| Methylomonas aminofaciens 77a | Q48907 | - |
- |
| Methylomonas sp. | - |
- |
- |
| Methylomonas sp. M15 / DSM 580 | - |
- |
- |
| Methylophilus methylotrophus | - |
- |
- |
| Mycobacterium gastri | - |
- |
- |
| Mycobacterium gastri MB19 | - |
- |
- |
| Pyrococcus horikoshii | - |
strain OT3 | - |
| Pyrococcus horikoshii OT-3 | - |
strain OT3 | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| D-ribulose 5-phosphate + formaldehyde | - |
Methanosarcina barkeri | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Bacillus sp. (in: Bacteria) | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methylophilus methylotrophus | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Pyrococcus horikoshii | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methanosarcina mazei | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methylomonas sp. | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Mycobacterium gastri | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methylomonas aminofaciens | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methylococcus capsulatus | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Mycobacterium gastri MB19 | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methylomonas sp. M15 / DSM 580 | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Bacillus sp. (in: Bacteria) C1 | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Pyrococcus horikoshii OT-3 | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
| D-ribulose 5-phosphate + formaldehyde | - |
Methylomonas aminofaciens 77a | D-arabino-hex-3-ulose 6-phosphate | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homodimer | - |
Methanosarcina barkeri |
| homodimer | - |
Pyrococcus horikoshii |
| homodimer | - |
Methanosarcina mazei |
| homodimer | 2 * 22000 | Methylomonas sp. |
| homodimer | 2 * 27000 | Bacillus sp. (in: Bacteria) |
| homodimer | 2 * 23000 | Methylomonas aminofaciens |
| homodimer | 2 * 22500 | Methylophilus methylotrophus |
| homodimer | 2 * 24000 | Mycobacterium gastri |
| homohexamer | 6 * 49000 | Methylococcus capsulatus |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-hexulose-6-phosphate synthase | - |
Methanosarcina barkeri |
| 3-hexulose-6-phosphate synthase | - |
Bacillus sp. (in: Bacteria) |
| 3-hexulose-6-phosphate synthase | - |
Methylophilus methylotrophus |
| 3-hexulose-6-phosphate synthase | - |
Methanosarcina mazei |
| 3-hexulose-6-phosphate synthase | - |
Methylomonas sp. |
| 3-hexulose-6-phosphate synthase | - |
Mycobacterium gastri |
| 3-hexulose-6-phosphate synthase | - |
Methylomonas aminofaciens |
| 3-hexulose-6-phosphate synthase | - |
Methylococcus capsulatus |
| 3-hexulose-6-phosphate synthase | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Pyrococcus horikoshii |
| HPS | - |
Pyrococcus horikoshii |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Methanosarcina barkeri |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Bacillus sp. (in: Bacteria) |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Methylophilus methylotrophus |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Methanosarcina mazei |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Methylomonas sp. |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Mycobacterium gastri |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Methylomonas aminofaciens |
| HPS | 3-hexulose-6-phosphate synthase and 6-phospho-3-hexuloisomerase activities are expressed constitutively in archea | Methylococcus capsulatus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 90 | - |
the recombinant enzyme is stable at 90°C | Methanosarcina barkeri |
| 90 | - |
the recombinant enzyme is stable at 90°C | Bacillus sp. (in: Bacteria) |
| 90 | - |
the recombinant enzyme is stable at 90°C | Methylophilus methylotrophus |
| 90 | - |
the recombinant enzyme is stable at 90°C | Pyrococcus horikoshii |
| 90 | - |
the recombinant enzyme is stable at 90°C | Methanosarcina mazei |
| 90 | - |
the recombinant enzyme is stable at 90°C | Methylomonas sp. |
| 90 | - |
the recombinant enzyme is stable at 90°C | Mycobacterium gastri |
| 90 | - |
the recombinant enzyme is stable at 90°C | Methylomonas aminofaciens |
| 90 | - |
the recombinant enzyme is stable at 90°C | Methylococcus capsulatus |
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