Literature summary for 4.1.2.38 extracted from

Sopaci, S.B.; Simsek, I.; Tural, B.; Volkan, M.; Demir, A.S.
Carboligation reactions with benzaldehyde lyase immobilized on superparamagnetic solid support (2009), Org. Biomol. Chem., 7, 1658-1664.

Search for more literature for 4.1.2.38

Activating Compound

Activating Compound	Comment	Organism	Structure
benzaldehyde	no activity with 200 mg m/L benzaldehyde. Reaction conducted with 50 mg benzaldehyde results in a 90% conversion after 45 min	synthetic construct

Cloned(Commentary)

Cloned (Comment)	Organism
expressed in Escherichia coli BL21(DE3)pLysS containing the pUC19-BAL-HIS construct	synthetic construct

Inhibitors

Inhibitors	Comment	Organism	Structure
Benzoin	product inhibition	synthetic construct
additional information	immobilization of BAL to surface-modified magnetic particles with affinity ligand binding	synthetic construct

Metals/Ions

Metals/Ions	Comment	Organism	Structure
Mg2+	-	synthetic construct

Organism

Organism	UniProt	Comment	Textmining
synthetic construct	-	-	-

Purification (Commentary)

Purification (Comment)	Organism
by Ni2+-NTA affinity column, to purity	synthetic construct

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
benzaldehyde + benzaldehyde	immobilized BAL mediated reaction, conversion is low	synthetic construct	(R)-benzoin	i.e. 2-hydroxy-1,2-diphenylethan-1-one	?
additional information	(R)-benzoin and acetaldehyde are converted in an immobilized BAL mediated reaction to 2-hydroxy-1,2-diphenylethan-1-one and (R)-2-hydroxy-1-phenylpropanone	synthetic construct	?	-	?
p-anisaldehyde + dimethoxy acetaldehyde	immobilized BAL mediated reaction	synthetic construct	(R)-2-hydroxy-3,3-dimethoxy-1-(4-methoxyphenyl)propan-1-one	-	?

Synonyms

Synonyms	Comment	Organism
BAL	-	synthetic construct
benzaldehyde lyase	-	synthetic construct

Cofactor

Cofactor	Comment	Organism	Structure
thiamine diphosphate	-	synthetic construct

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Release 2023.1 (January 2023)