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Literature summary for 4.1.2.27 extracted from
- Sphingosine-1-phosphate lyase SPL is an endoplasmic reticulum-resident, integral membrane protein with the pyridoxal 5'-phosphate binding domain exposed to the cytosol (2004), Biochem. Biophys. Res. Commun., 325, 338-343.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | the large hydrophilic domain containing the active site is facing the cytosol | Mus musculus | 5783 | - |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Mus musculus | - |
recombinant enzyme with N-terminal HA-tag | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| heart | mRNA expression is temporally regulated during embryonal development | Mus musculus | - |
| liver | mRNA expression is temporally regulated during embryonal development | Mus musculus | - |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Mus musculus |  |
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