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Literature summary for 4.1.2.27 extracted from
- Sphingosine-phosphate lyase enhances stress-induced ceramide generation and apoptosis (2004), J. Biol. Chem., 279, 1281-1290.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| fusion protein with green fluorescence protein, expressed in HEK293 cells | Homo sapiens |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| endoplasmic reticulum | - |
Homo sapiens | 5783 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 63480 | - |
calculated from amino acid sequence | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Homo sapiens | role in ceramide metabolism and cell fate | ? | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | O95470 | - |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | role in ceramide metabolism and cell fate | Homo sapiens | ? | - |
? | |
| sphingosine 1-phosphate | - |
Homo sapiens | phosphoethanolamine + palmitaldehyde | - |
ir | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Homo sapiens |
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Release 2023.1 (January 2023)
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