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Literature summary for 4.1.1.99 extracted from
- Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production (2016), Metab. Eng., 34, 25-35 .
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | isopentenol production in Escherichia coli by utilizing phosphomevalonate decarboxylase and Escherchia coli-endogenous phosphatase AphA. The enzymes bypass the isopentenyl diphosphate mevalonate pathways, have reduced energetic requirements, are further decoupled from intrinsic regulation, and are free from isopentenyl diphosphate-related toxicity. Reduced aeration rate has less impact on the bypass pathway than the original mevalonate pathway. The performance of the bypass pathway is primarily determined by the activity of phosphomevalonate decarboxylase | Haloferax volcanii |
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expression in Escherichia coli | Haloferax volcanii |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Haloferax volcanii | D4GXZ3 | - |
- |
| Haloferax volcanii DSM 3757 | D4GXZ3 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| MvaD | - |
Haloferax volcanii |
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Release 2023.1 (January 2023)
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