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Literature summary for 4.1.1.90 extracted from
- Effects of gamma-glutamyl carboxylase gene polymorphism (R325Q) on the association between dietary vitamin K intake and gamma-carboxylation of osteocalcin in young adults (2013), Asia Pac. J. Clin. Nutr., 22, 646-654.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| R325Q | the mutation is associated with the bone mineral density | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O | Homo sapiens | - |
peptidyl-glutamate + CO2 + O2 + phylloquinone | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| blood | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| peptidyl-4-carboxyglutamate + 2,3-epoxyphylloquinone + H2O | - |
Homo sapiens | peptidyl-glutamate + CO2 + O2 + phylloquinone | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| gamma-glutamyl carboxylase | - |
Homo sapiens |
| GGCX | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| vitamin K | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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