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Literature summary for 4.1.1.90 extracted from

  • Wang, T.; Yang, J.; Qiao, J.; Liu, J.; Guo, X.; Ye, Z.
    Activity and expression of vitamin K-dependent gamma-glutamyl carboxylase in patients with calcium oxalate urolithiasis (2010), Urol. Int., 85, 94-99.
    View publication on PubMed
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Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
epithelial cell
-
 Homo sapiens
-
renal tubule
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
gamma-glutamyl carboxylase
-
 Homo sapiens
GGCX
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens GGCX mRNA in the urolithiasic group is lower than that in the normal control group, which is on average 7.86fold underexpressed in the urolithiasic group compared to the normal control group. Protein expression of GGCX in the urolithiasic group is weaker than that in the control groups down

General Information

General Information Comment Organism
physiological function relevance between the defect of GGCX and urolithasis. Decreased activity and production of GGCX between calcium oxalate urolithiasis patients and control patients. GGCX may play an important role in the formation of calcium oxalate. The decreased expression of GGCX may lead to the defect of activity, and may result in the declined ability of calcium oxalate of urinary prothrombin fragment 1 Homo sapiens