Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
endoplasmic reticulum | - |
Bos taurus | 5783 | - |
membrane | integral membrane protein | Bos taurus | 16020 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
94000 | - |
SDS-PAGE | Bos taurus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Bos taurus | enzyme required for the posttranslational modification of vitamin K-dependent proteins | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bos taurus | Q07175 | - |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
4-benzoyl-L-phenylalanine + CO2 + O2 + vitamin K hydroquinone | BPA | Bos taurus | ? + vitamin K epoxide + H2O | - |
? | |
CDADWVEGYSMEYLSR + CO2 + O2 + vitamin K hydroquinone | CDADWVEGYSMEYLSR | Bos taurus | ? + vitamin K epoxide + H2O | - |
? | |
CGRPSLEQLAQEVTYA + CO2 + O2 + vitamin K hydroquinone | CGRPSLEQLAQEVTYA | Bos taurus | ? + vitamin K epoxide + H2O | - |
? | |
L-glutamate + CO2 + O2 + vitamin K hydroquinone | vitamin K epoxide must be recycled to vitamin K hydroquinone by the enzyme epoxide reductase for the reaction to continue | Bos taurus | gamma-carboxy L-glutamate + vitamin K epoxide + H2O | - |
? | |
additional information | enzyme required for the posttranslational modification of vitamin K-dependent proteins | Bos taurus | ? | - |
? | |
pro-FIX19 + CO2 + O2 + vitamin K hydroquinone | pro-FIX19: peptide comprising residues of human factor IX AVFLDHENANKILNRPKRY | Bos taurus | ? + vitamin K epoxide + H2O | - |
? | |
pro-FIX19-16BPA + CO2 + O2 + vitamin K hydroquinone | pro-FIX19-16BPA: peptide comprising residues TVBLDHENANKILNRPKRY | Bos taurus | ? + vitamin K epoxide + H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
? | x * 94000, SDS-PAGE | Bos taurus |
More | binding site in the carboxyl half of the gamma-glutamyl carboxylase. Carboxylase may be cleaved by trypsin into an amino-terminal 30 kDa and a carboxyl-terminal 60 kDa fragment joined by disulfide bond(s), and the propeptide binds to the 60 kDa fragment | Bos taurus |
Synonyms | Comment | Organism |
---|---|---|
gamma-glutamyl carboxylase | - |
Bos taurus |
glutamate carboxylase | - |
Bos taurus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
vitamin K | - |
Bos taurus |