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Literature summary for 4.1.1.90 extracted from
- The submicrosomal site for the conversion of prothrombin precursor to biologically active prothrombin in rat liver (1977), Biochim. Biophys. Acta, 499, 181-193.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| CsCl | - |
Rattus norvegicus |  |
| deoxycholate | - |
Rattus norvegicus | |
| additional information | NADH, dithiothreitol, and ATP deficiency decrease enzyme activity | Rattus norvegicus | |
| p-chloromercuribenzoate | 97% inhibition with 1.25 mM and at 5 mM the reaction is completely inhibited | Rattus norvegicus | |
| sucrose | - |
Rattus norvegicus | |
| Trypsin | - |
Rattus norvegicus | |
| warfarin | - |
Rattus norvegicus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| microsome | - |
Rattus norvegicus | - |
- |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | O88496 | Wistar strain male albino rats, vitamin K-deficient or warfarin-treated | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| glutamate carboxylase | - |
Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| vitamin K | aquamephyton | Rattus norvegicus | |
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Release 2023.1 (January 2023)
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