Literature summary for 4.1.1.9 extracted from

Koves, T.R.; Ussher, J.R.; Noland, R.C.; Slentz, D.; Mosedale, M.; Ilkayeva, O.; Bain, J.; Stevens, R.; Dyck, J.R.; Newgard, C.B.; Lopaschuk, G.D.; Muoio, D.M.
Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance (2008), Cell Metab., 7, 45-56.

Search for more literature for 4.1.1.9

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
mitochondrion	-	Mus musculus	5739	-

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining
skeletal muscle	-	Mus musculus	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
Malonyl-CoA	MCD degrades the natural CPT1 inhibitor malonyl-CoA and thereby facilitates fatty acid import into mitochondria	Mus musculus	Acetyl-CoA + CO2	-	?

Synonyms

Synonyms	Comment	Organism
MCD	-	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)