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Literature summary for 4.1.1.81 extracted from

  • Cheong, C.G.; Bauer, C.B.; Brushaber, K.R.; Escalante-Semerena, J.C.; Rayment, I.
    Three-dimensional structure of the L-threonine-O-3-phosphate decarboxylase (CobD) enzyme from Salmonella enterica (2002), Biochemistry, 41, 4798-4808.
    View publication on PubMed
Search for more literature for 4.1.1.81

Cloned(Commentary)

Cloned (Comment) Organism
overproduced in Escherichia coli Salmonella enterica

Crystallization (Commentary)

Crystallization (Comment) Organism
crystals grown from hanging drops, CobD crystallizes in orthorhombic space group I222, unit cell dimensions a = 67.96 A, b = 101.55 A, and c = 117.23 A Salmonella enterica

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
40800
-
-
 Salmonella enterica

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-threonine O-3-phosphate Salmonella enterica
-
 (R)-1-aminopropan-2-yl phosphate + CO2
-
 ?
L-threonine O-3-phosphate Salmonella enterica biosynthetic pathway of cobalamin, essential cofactor for many living organisms, only synthesized de novo by bacteria and archaea (R)-1-aminopropan-2-yl phosphate + CO2 precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin ?

Organism

Organism UniProt Comment Textmining
no activity in eukaryota
-
-
-
Salmonella enterica
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Salmonella enterica

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-threonine O-3-phosphate
-
 Salmonella enterica (R)-1-aminopropan-2-yl phosphate + CO2
-
 ?
L-threonine O-3-phosphate biosynthetic pathway of cobalamin, essential cofactor for many living organisms, only synthesized de novo by bacteria and archaea Salmonella enterica (R)-1-aminopropan-2-yl phosphate + CO2 precursor for the linkage between the nucleotide loop and the corrin ring in cobalamin ?

Subunits

Subunits Comment Organism
dimer
-
 Salmonella enterica

Synonyms

Synonyms Comment Organism
CobD
-
 Salmonella enterica
CobD gene product
-
 Salmonella enterica