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Literature summary for 4.1.1.76 extracted from

  • Miyamoto, K.; Tsutsumi, T.; Terao, Y.; Ohta, H.
    Stereochemistry of decarboxylation of arylmalonate catalyzed by mutant enzymes (2007), Chem. Lett., 36, 656-657.
No PubMed abstract available

Protein Variants

Protein Variants Comment Organism
G74C results in the formation of racemic products Bordetella bronchiseptica
G74C/C188S results in the inversion of enantioselectivity to give (S)-alpha-arylpropionate Bordetella bronchiseptica
G74C/S36N/G74C/C188S enhanced activity compared to G74C/C188S Bordetella bronchiseptica
S36N/G74C/C188S enhanced activity compared to G74C/C188S Bordetella bronchiseptica

Organism

Organism UniProt Comment Textmining
Bordetella bronchiseptica
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
alpha-methyl-alpha-(beta-naphthyl)malonate
-
Bordetella bronchiseptica alpha-(beta-naphthyl)propionate + CO2
-
?
Phenylmalonate
-
Bordetella bronchiseptica Phenylacetate + CO2
-
?

Synonyms

Synonyms Comment Organism
AMDase
-
Bordetella bronchiseptica