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Literature summary for 4.1.1.65 extracted from

  • Chan, E.Y.; McQuibban, G.A.
    Phosphatidylserine decarboxylase 1 (Psd1) promotes mitochondrial fusion by regulating the biophysical properties of the mitochondrial membrane and alternative topogenesis of mitochondrial genome maintenance protein 1 (Mgm1) (2012), J. Biol. Chem., 287, 40131-40139.
    View publication on PubMedView publication on EuropePMC
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Localization

Localization Comment Organism GeneOntology No. Textmining
mitochondrion
-
 Saccharomyces cerevisiae 5739
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Phosphatidyl-L-serine Saccharomyces cerevisiae
-
 Phosphatidylethanolamine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phosphatidyl-L-serine
-
 Saccharomyces cerevisiae Phosphatidylethanolamine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
PSD1
-
 Saccharomyces cerevisiae

General Information

General Information Comment Organism
malfunction the psd1-deficient strain shows reduced fusion kinetics and also has impaired mitochondrial activity such as oxidative phosphorylation and reduced mitochondrial ATP levels. The loss of Psd1 also impairs the biogenesis of s-Mgm1, a protein essential for mitochondrial fusion Saccharomyces cerevisiae
physiological function Psd1 is required for normal mitochondrial morphology, proper mitochondrial fusion during yeast mating, and proper mitochondrial activity Saccharomyces cerevisiae