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Literature summary for 4.1.1.65 extracted from

  • Luo, J.; Matsuo, Y.; Gulis, G.; Hinz, H.; Patton-Vogt, J.; Marcus, S.
    Phosphatidylethanolamine is required for normal cell morphology and cytokinesis in the fission yeast Schizosaccharomyces pombe (2009), Eukaryot. Cell, 8, 790-799.
    View publication on PubMedView publication on EuropePMC
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Organism

Organism UniProt Comment Textmining
Schizosaccharomyces pombe
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Schizosaccharomyces pombe SP870
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Phosphatidyl-L-serine
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 Schizosaccharomyces pombe Phosphatidylethanolamine + CO2
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 ?
Phosphatidyl-L-serine
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 Schizosaccharomyces pombe SP870 Phosphatidylethanolamine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
PSD
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 Schizosaccharomyces pombe

General Information

General Information Comment Organism
malfunction mutants carrying deletions in any one or two psd genes are viable in complex rich medium and synthetic defined minimal medium. However, mutants carrying deletions in all three psd genes (psd1-3DELTA mutants) grow slowly in rich medium and are inviable in minimal medium. psd1-3_DELTAcells appear morphologically indistinguishable from wild type cells in medium supplemented with ethanolamine, but when cultured in nonsupplemented medium, they produce high frequencies of abnormally shaped cells as well as cells exhibiting severe septation defects, including multiple, mispositioned, deformed, and misoriented septa. Schizosaccharomyces pombe
physiological function the psd1, psd2, and psd3 gene products share overlapping functions essential for the normal growth of Schizosaccharomyces pombe cells Schizosaccharomyces pombe