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Literature summary for 4.1.1.50 extracted from
- Inhibition of S-adenosylmethionine decarboxylase by inhibitor SAM486A connects polyamine metabolism with p53-Mdm2-Akt/protein kinase B regulation and apoptosis in neuroblastoma (2009), Mol. Cancer Ther., 8, 2067-2075.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| SAM486A | also known as CGP48664 | Homo sapiens |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| IMR-32 cell | - |
Homo sapiens | - |
| neuroblastoma cell | - |
Homo sapiens | - |
| SH-SY5Y cell | - |
Homo sapiens | - |
| SK-N-SH cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| S-adenosyl-L-methionine | - |
Homo sapiens | (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| AdoMetDC | - |
Homo sapiens |
| S-Adenosylmethionine decarboxylase | - |
Homo sapiens |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Homo sapiens | |
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Release 2023.1 (January 2023)
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