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Literature summary for 4.1.1.50 extracted from

  • Jไnne, J.; Alhonen-Hongisto, L.; Nikula, P.; Elo, H.
    S-Adenosylmethionine decarboxylase as target of chemotherapy (1985), Adv. Enzyme Regul., 24, 125-139.
    View publication on PubMed

Application

Application Comment Organism
pharmacology the enzyme is a target for cancer chemotherapy Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
Glyoxal bis(guanylhydrazone)
-
Mus musculus
methylglyoxal bis(guanylhydrazone)
-
Mus musculus

Organism

Organism UniProt Comment Textmining
Mus musculus
-
-
-

Source Tissue

Source Tissue Comment Organism Textmining
Ehrlich ascites carcinoma cell
-
Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
S-adenosyl-L-methionine
-
Mus musculus (5-deoxy-5-adenosyl)(3-aminopropyl)methylsulfonium salt + CO2
-
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