Cloned (Comment) | Organism |
---|---|
expression in COS-7 cells | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
mono (2-ethyl hexyl) phthalate | 90% inhibition of ACMSD activity in the presence of 3 mmol/l mono (2-ethyl hexyl) phthalate, inhibition is reversible | Rattus norvegicus | |
mono (2-ethylhexyl) phthalate | 92% inhibition of ACMSD activity in the presence of 3 mmol/l mono (2-ethyl hexyl) phthalate, inhibition is reversible | Homo sapiens | |
mono (2-ethylhexyl) phthalate | 93% inhibition of ACMSD activity in the presence of 3 mmol/l mono (2-ethyl hexyl) phthalate | Mus musculus | |
mono-n-butyl phthalate | 18% inhibition of ACMSD activity in the presence of 3 mmol/l mono-n-butyl phthalate | Homo sapiens | |
mono-n-butyl phthalate | 15% inhibition of ACMSD activity in the presence of 3 mmol/l mono-n-butyl phthalate | Mus musculus | |
mono-n-butyl phthalate | 20% inhibition of ACMSD activity in the presence of 3 mmol/l mono-n-butyl phthalate | Rattus norvegicus | |
mono-n-hexyl phthalate | 84% inhibition of ACMSD activity in the presence of 3 mmol/l mono-n-hexyl phthalate | Homo sapiens | |
mono-n-hexyl phthalate | 64% inhibition of ACMSD activity in the presence of 3 mmol/l mono-n-hexyl phthalate | Mus musculus | |
mono-n-hexyl phthalate | 60% inhibition of ACMSD activity in the presence of 3 mmol/l mono-n-hexyl phthalate | Rattus norvegicus | |
additional information | not inhibited by monoethyl phthalate | Homo sapiens | |
additional information | not inhibited by monoethyl phthalate | Mus musculus | |
additional information | not inhibited by monoethyl phthalate | Rattus norvegicus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Mus musculus | - |
- |
- |
Rattus norvegicus | - |
Wistar rat | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
kidney | - |
Mus musculus | - |
liver | - |
Rattus norvegicus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
3.07 micromol/h/g kidney, enzyme assay performed at 25°C, pH 8.0 and 50 mmol/l Tris-acetate buffer | Mus musculus |
additional information | - |
9.3 micromol/h/g liver, enzyme assay performed at 25°C, pH 8.0 and in 50 mmol/l Tris-acetate buffer | Rattus norvegicus |
0.36 | - |
enzyme assay performed at 25°C, pH 8.0 and 50 mmol/l Tris-acetate buffer | Homo sapiens |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | - |
Mus musculus | 2-aminomuconate-6-semialdehyde + CO2 | - |
? | |
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | - |
Homo sapiens | 2-aminomuconate-6-semialdehyde + CO2 | - |
? | |
2-amino-3-(3-oxoprop-1-en-1-yl)but-2-enedioate | - |
Rattus norvegicus | 2-aminomuconate-6-semialdehyde + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ACMSD | - |
Mus musculus |
ACMSD | - |
Homo sapiens |
ACMSD | - |
Rattus norvegicus |
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase | - |
Mus musculus |
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase | - |
Homo sapiens |
alpha-amino-beta-carboxymuconate-epsilon-semialdehyde decarboxylase | - |
Rattus norvegicus |