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Literature summary for 4.1.1.43 extracted from

  • Fujioka, M.; Morino, Y.; Wada, H.
    Metabolism of phenylalanine. (Achromobacter eurydice) (1970), Methods Enzymol., 17, 585-596.
No PubMed abstract available

Inhibitors

Inhibitors Comment Organism Structure
Cu2+
-
Acinetobacter sp.
EDTA
-
Acinetobacter sp.
p-hydroxyphenylpyruvate
-
Acinetobacter sp.
PCMB
-
Acinetobacter sp.
Zn2+
-
Acinetobacter sp.

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0051
-
phenylpyruvate
-
Acinetobacter sp.

Metals/Ions

Metals/Ions Comment Organism Structure
Mg2+ required Acinetobacter sp.
Mn2+ can partially replace Mg2+ Acinetobacter sp.

Organism

Organism UniProt Comment Textmining
Acinetobacter sp.
-
other name: Achromobacter eurydice
-

Purification (Commentary)

Purification (Comment) Organism
-
Acinetobacter sp.

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
0.67
-
-
Acinetobacter sp.

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2-Oxo-gamma-ethylthiobutanoate
-
Acinetobacter sp. beta-Ethiopropanal + CO2
-
?
2-Oxohexanoate
-
Acinetobacter sp. Pentanal + CO2
-
?
4-methylthio-2-oxobutanoate
-
Acinetobacter sp. beta-methiopropanal + CO2
-
?
Indolepyruvate
-
Acinetobacter sp. Indoleethanal + CO2
-
?
Phenylpyruvate
-
Acinetobacter sp. Phenylacetaldehyde + CO2
-
?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
7.6
-
-
Acinetobacter sp.

Cofactor

Cofactor Comment Organism Structure
thiamine diphosphate Km: 0.0013-0.0017 mM Acinetobacter sp.