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Literature summary for 4.1.1.37 extracted from

  • Chaufan, G.; Corvi, M.; Armesto, A.; San Martin de Viale, L.C.; Luquet, C.; Rios de Molina, M.
    Comparison between crab hepatopancreas and rat liver uroporphyrinogen decarboxylase (2002), Comp. Biochem. Physiol. B, 133, 251-256.
    View publication on PubMed
Search for more literature for 4.1.1.37

Application

Application Comment Organism
agriculture first step to establish this enzyme as a possible biomarker for environmental contamination Rattus norvegicus
agriculture first step to establish this enzyme as a possible biomarker for environmental contamination Neohelice granulata

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0015
-
 8-carboxylporphyrinogen pH 6.8, 37°C Rattus norvegicus
0.0105
-
 8-carboxylporphyrinogen pH 6.8, 37°C Neohelice granulata

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
48000
-
 gel filtration Neohelice granulata

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
Uroporphyrinogen III Rattus norvegicus fifth enzyme of the haem biosynthetic pathway Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III Neohelice granulata fifth enzyme of the heme biosynthetic pathway Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III Rattus norvegicus Wistar fifth enzyme of the haem biosynthetic pathway Coproporphyrinogen III + 4 CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Neohelice granulata
-
 intertidal grapsid crab
-
Rattus norvegicus
-
 Wistar strain
-
Rattus norvegicus
-
 rat, Wistar
-
Rattus norvegicus Wistar
-
 Wistar strain
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus
-
 Neohelice granulata

Source Tissue

Source Tissue Comment Organism Textmining

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
8-carboxylporphyrinogen
-
 Rattus norvegicus coproporphyrinogen(4-COOH) + CO2
-
 ?
8-carboxylporphyrinogen
-
 Neohelice granulata coproporphyrinogen(4-COOH) + CO2
-
 ?
8-carboxylporphyrinogen
-
 Rattus norvegicus Wistar coproporphyrinogen(4-COOH) + CO2
-
 ?
Uroporphyrinogen III
-
 Rattus norvegicus Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III
-
 Neohelice granulata Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III fifth enzyme of the haem biosynthetic pathway Rattus norvegicus Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III fifth enzyme of the heme biosynthetic pathway Neohelice granulata Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III
-
 Rattus norvegicus Wistar Coproporphyrinogen III + 4 CO2
-
 ?
Uroporphyrinogen III fifth enzyme of the haem biosynthetic pathway Rattus norvegicus Wistar Coproporphyrinogen III + 4 CO2
-
 ?

Synonyms

Synonyms Comment Organism
ch-UroD
-
 Neohelice granulata
rl-UroD
-
 Rattus norvegicus
UroD
-
 Rattus norvegicus
UroD
-
 Neohelice granulata
uroporphyrinogen decarboxylase
-
 Rattus norvegicus
uroporphyrinogen decarboxylase
-
 Neohelice granulata

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
47
-
-
 Rattus norvegicus
47
-
-
 Neohelice granulata

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
-
 70 activity increases with temperature up to 47°C, decreases at 53°C Rattus norvegicus
-
 70 activity increases with temperature up to 47°C, decreases at 53°C Neohelice granulata

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.8
-
-
 Rattus norvegicus
7.2
-
-
 Neohelice granulata

pH Range

pH Minimum pH Maximum Comment Organism
6.1 7.9
-
 Rattus norvegicus
6.4 7.9
-
 Neohelice granulata