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Literature summary for 4.1.1.33 extracted from
- Modification of the radiochemical assay of rat liver mevalonate-5-diphosphate decarboxylase and induction and stabilization of the activity (1991), Biochem. Biophys. Res. Commun., 181, 1449-1455.
General Stability
| General Stability | Organism |
|---|---|
| stabilized by phenylmethylsulfonyl fluoride, aprotinin and leupeptin | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 5-diphosphomevalonate | Rattus norvegicus | enzyme activity is increased by 5fold after feeding young rats 2.5% cholestyramine for ten days to four weeks | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| -20°C or -73°C, rat liver homogenate with 0.1 mM leupeptin, 0.75 mg/l aprotinin, 0.1 mM phenylmethylsulfonyl fluoride, 15 mM EDTA, 15 mM EGTA, stable for over 3 months | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 5-diphosphomevalonate | - |
Rattus norvegicus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| ATP + 5-diphosphomevalonate | enzyme activity is increased by 5fold after feeding young rats 2.5% cholestyramine for ten days to four weeks | Rattus norvegicus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
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