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Literature summary for 4.1.1.33 extracted from
- Mevalonate decarboxylation in lemon grass leaves (1985), Phytochemistry, 24, 2569-2571.
No PubMed abstract available
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| ferulate | - |
Cymbopogon citratus |  |
| p-coumarate | - |
Cymbopogon citratus | |
| phloroglucinol carboxylic acid | - |
Cymbopogon citratus | |
| protocatechuate | - |
Cymbopogon citratus | |
| Resorcyclic acid | - |
Cymbopogon citratus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.01 | - |
5-diphosphomevalonate | - |
Cymbopogon citratus | |
| 0.3 | - |
GTP | - |
Cymbopogon citratus | |
| 0.47 | - |
CTP | - |
Cymbopogon citratus | |
| 1.66 | - |
ATP | - |
Cymbopogon citratus | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | exclusively | Cymbopogon citratus | 5829 | - |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | required | Cymbopogon citratus | |
| Mn2+ | can partially replace Mg2+ | Cymbopogon citratus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Arachis hypogaea | - |
- |
- |
| Cymbopogon citratus | - |
- |
- |
| Oryza sativa | - |
- |
- |
| Pisum sativum | - |
- |
- |
| Vigna radiata | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| leaf | - |
Arachis hypogaea | - |
| leaf | seasonal variations in activity, maximal activity in hot summer months, in the cold winter months the activity cannot be detected | Cymbopogon citratus | - |
| seedling | - |
Pisum sativum | - |
| seedling | - |
Arachis hypogaea | - |
| seedling | - |
Vigna radiata | - |
| seedling | - |
Oryza sativa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| ATP + 5-diphosphomevalonate | - |
Pisum sativum | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| ATP + 5-diphosphomevalonate | - |
Arachis hypogaea | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| ATP + 5-diphosphomevalonate | - |
Vigna radiata | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| ATP + 5-diphosphomevalonate | - |
Oryza sativa | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| ATP + 5-diphosphomevalonate | high specificity for ATP | Cymbopogon citratus | ADP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| CTP + 5-diphosphomevalonate | about 10% of the activity with ATP | Cymbopogon citratus | CDP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
| GTP + 5-diphosphomevalonate | about 15% of the activity with ATP | Cymbopogon citratus | GDP + phosphate + isopentenyl diphosphate + CO2 | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6 | - |
- |
Cymbopogon citratus |
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