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Literature summary for 4.1.1.31 extracted from

  • Paulus, J.K.; Niehus, C.; Groth, G.
    Evolution of C4 phosphoenolpyruvate carboxylase: enhanced feedback inhibitor tolerance is determined by a single residue (2013), Mol. Plant, 6, 1996-1999.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
R884E the mutant is clearly less sensitive towards malate compared to the wild type enzyme Flaveria pringlei
R884Q the mutant is clearly less sensitive towards malate compared to the wild type enzyme Flaveria pringlei
R884S the mutant is clearly less sensitive towards malate compared to the wild type enzyme Flaveria pringlei

Inhibitors

Inhibitors Comment Organism Structure
malate
-
Flaveria pringlei
malate
-
Flaveria trinervia

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
phosphoenolpyruvate + HCO3- Flaveria trinervia
-
phosphate + oxaloacetate
-
?
phosphoenolpyruvate + HCO3- Flaveria pringlei
-
phosphate + oxaloacetate
-
?

Organism

Organism UniProt Comment Textmining
Flaveria pringlei Q01647
-
-
Flaveria trinervia
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
phosphoenolpyruvate + HCO3-
-
Flaveria trinervia phosphate + oxaloacetate
-
?
phosphoenolpyruvate + HCO3-
-
Flaveria pringlei phosphate + oxaloacetate
-
?

Synonyms

Synonyms Comment Organism
PEPC
-
Flaveria trinervia
PEPC
-
Flaveria pringlei

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
0.0000026
-
wild type enzyme, pH and temperature not specified in the publication Flaveria pringlei malate
4.3
-
mutant enzyme R884Q, pH and temperature not specified in the publication Flaveria pringlei malate
6.6
-
mutant enzyme R884S, pH and temperature not specified in the publication Flaveria pringlei malate
8.7
-
wild type enzyme, pH and temperature not specified in the publication Flaveria trinervia malate
15.7
-
mutant enzyme R884E, pH and temperature not specified in the publication Flaveria pringlei malate