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Literature summary for 4.1.1.29 extracted from

  • Liu, S.; Liu, Y.; Ma, Q.; Cui, S.; Liu, J.
    Expression and localization of cysteine sulfinate decarboxylase in major salivary glands of male mice (2015), Arch. Oral Biol., 60, 615-621 .
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
real-time PCR enzyme expression analysis Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
3-sulfino-L-alanine Mus musculus
-
hypotaurine + CO2
-
?

Organism

Organism UniProt Comment Textmining
Mus musculus Q9DBE0
-
-

Source Tissue

Source Tissue Comment Organism Textmining
central nervous system
-
Mus musculus
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kidney
-
Mus musculus
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liver highest expression level Mus musculus
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additional information the enzyme is mainly located in the excretory ducts (EDs) and interlobular duct (IL) of submandibular gland (SMG) and ED in sublingual gland (SLG), respectively. The relative levels of CSD mRNA increase from the submandibular gland (SMG) to the sublingual gland (SLG) and parotid gland (PG), but the levels of the CSD protein are the opposite. Immunofluorescence for the expression of CSD and alpha-SMA in SMG, SLG, and PG Mus musculus
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muscle
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Mus musculus
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salivary gland CSD messenger RNA (mRNA) and protein are expressed in the major salivary glands of male mice. The relative levels of CSD mRNA increase from the submandibular gland (SMG) to the sublingual gland (SLG) and parotid gland (PG), but the levels of the CSD protein are the opposite Mus musculus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
3-sulfino-L-alanine
-
Mus musculus hypotaurine + CO2
-
?

Synonyms

Synonyms Comment Organism
CSAD
-
Mus musculus
CSD
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Mus musculus
Cysteine sulfinate decarboxylase
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Mus musculus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Mus musculus

General Information

General Information Comment Organism
physiological function CSD is the rate-limiting enzyme of taurine biosynthesis Mus musculus