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Literature summary for 4.1.1.29 extracted from
- Cysteinesulfinate metabolism. Altered partitioning between transamination and decarboxylation following administration of beta-methyleneaspartate (1983), J. Biol. Chem., 258, 1591-1598.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| beta-Methyleneaspartate | potent irreversible | Rattus norvegicus |  |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.2 | - |
cysteine sulfinic acids | - |
Rattus norvegicus | |
| 11 | - |
Asp | - |
Rattus norvegicus | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Cysteine sulfinate | Rattus norvegicus | the enzyme initiates a pathway leading to taurine | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| liver | - |
Rattus norvegicus | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Cysteine sulfinate | the enzyme initiates a pathway leading to taurine | Rattus norvegicus | ? | - |
? | |
| cysteine sulfinic acids | - |
Rattus norvegicus | ? | - |
? | |
| Glu | very slowly | Rattus norvegicus | 4-Aminobutanoate + CO2 | - |
? | |
| L-Asp | - |
Rattus norvegicus | beta-Ala + CO2 | - |
? | |
| L-Cysteine sulfinate | - |
Rattus norvegicus | 2-Aminoethane sulfinate + CO2 | - |
? | |
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Release 2023.1 (January 2023)
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