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Literature summary for 4.1.1.28 extracted from

  • Nakazawa, H.
    Inhibition of aromatic L-amino acid decarboxylase from Micrococcus percitreus by substrate analogs (1987), Agric. Biol. Chem., 51, 2531-2537 .
No PubMed abstract available
Search for more literature for 4.1.1.28

Inhibitors

Inhibitors Comment Organism Structure
2-Phenylethylamine competitive inhibition, 80% inhibition at 0.5 mM Micrococcus percitreus
3-Indoleacetamide 27% inhibition at 0.25 mM Micrococcus percitreus
3-Indolealdehyde 33% inhibition at 0.25 mM Micrococcus percitreus
alpha-methyl-DL-phenylalanine competitive inhibition Micrococcus percitreus
DL-m-tyrosine 50% inhibition at 4 mM Micrococcus percitreus
dopamine complete inhibition at 0.5 mM Micrococcus percitreus
epinephrine 30% inhibition at 4 mM Micrococcus percitreus
histamine 1% inhibition at 4 mM Micrococcus percitreus
L-Dopa competitive inhibition, 98% inhibition at 1 mM Micrococcus percitreus
L-histidine 5% inhibition at 4 mM Micrococcus percitreus
L-phenylalanine uncompetitive inhibition, 53% inhibition at 0.5 mM Micrococcus percitreus
L-tyrosine uncompetitive inhibition, 38% inhibition at 0.5 mM Micrococcus percitreus
additional information not inhibited by D-tryptophan, kynuramine, octopamine, and 3-indoleacetate Micrococcus percitreus
norepinephrine 40% inhibition at 4 mM Micrococcus percitreus
potassium bicarbonate 57% inhibition at 1 M Micrococcus percitreus
serotonin 2% inhibition at 4 mM Micrococcus percitreus
tryptamine 5% inhibition at 1 mM Micrococcus percitreus
tyramine competitive inhibition, 71% inhibition at 0.5 mM Micrococcus percitreus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-tryptophan Micrococcus percitreus
-
 tryptamine + CO2
-
 ?
L-tryptophan Micrococcus percitreus AJ 1065
-
 tryptamine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Micrococcus percitreus
-
-
-
Micrococcus percitreus AJ 1065
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-tryptophan
-
 Micrococcus percitreus tryptamine + CO2
-
 ?
L-tryptophan
-
 Micrococcus percitreus AJ 1065 tryptamine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
Aromatic L-amino acid decarboxylase
-
 Micrococcus percitreus