Cloned (Comment) | Organism |
---|---|
expressed in Escherichia coli | Sus scrofa |
KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.035 | - |
L-Dopa | pH 7.5, 25°C, anaerobiosis | Sus scrofa | |
0.038 | - |
L-5-hydroxytryptophan | pH 7.5, 25°C, anaerobiosis | Sus scrofa | |
0.0703 | - |
L-Dopa | pH 7.5, 25°C, aerobiosis | Sus scrofa | |
0.155 | - |
L-5-hydroxytryptophan | pH 7.5, 25°C, aerobiosis | Sus scrofa |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-tryptophan | Sus scrofa | - |
tryptamine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Sus scrofa | - |
pig | - |
Oxidation Stability | Organism |
---|---|
reaction specificity with D-aromatic amino acids does not change in presence or absence of O2, the reaction with L-aromatic amino acids seems to be affected by O2 | Sus scrofa |
Purification (Comment) | Organism |
---|---|
recombinant enzyme | Sus scrofa |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-5-hydroxytryptophan | - |
Sus scrofa | 5-hydroxytryptamine + CO2 | - |
? | |
L-Dopa | - |
Sus scrofa | dopamine + CO2 | - |
? | |
L-tryptophan | - |
Sus scrofa | tryptamine + CO2 | - |
? |
Subunits | Comment | Organism |
---|---|---|
homodimer | - |
Sus scrofa |
Synonyms | Comment | Organism |
---|---|---|
DDC | - |
Sus scrofa |
DOPA decarboxylase | - |
Sus scrofa |
Turnover Number Minimum [1/s] | Turnover Number Maximum [1/s] | Substrate | Comment | Organism | Structure |
---|---|---|---|---|---|
0.99 | - |
L-5-hydroxytryptophan | pH 7.5, 25°C, anaerobiosis | Sus scrofa | |
1.99 | - |
L-5-hydroxytryptophan | pH 7.5, 25°C, aerobiosis | Sus scrofa | |
2.57 | - |
L-Dopa | pH 7.5, 25°C, anaerobiosis | Sus scrofa | |
2.94 | - |
L-5-hydroxytryptophan | pH 7.5, 25°C, aerobiosis | Sus scrofa | |
3 | 6 | L-Dopa | pH 7.5, 25°C, anaerobiosis | Sus scrofa | |
3.13 | - |
L-Dopa | pH 7.5, 25°C, aerobiosis | Sus scrofa | |
4.26 | - |
L-Dopa | pH 7.5, 25°C, aerobiosis | Sus scrofa | |
6.08 | - |
L-5-hydroxytryptophan | pH 7.5, 25°C, anaerobiosis | Sus scrofa |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
pyridoxal 5'-phosphate | - |
Sus scrofa |