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Literature summary for 4.1.1.25 extracted from

  • Cole, S.H.; Carney, G.E.; McClung, C.A.; Willard, S.S.; Taylor, B.J.; Hirsh, J.
    Two functional but noncomplementing Drosophila tyrosine decarboxylase genes: distinct roles for neural tyramine and octopamine in female fertility (2005), J. Biol. Chem., 280, 14948-14955.
    View publication on PubMed

Cloned(Commentary)

Cloned (Comment) Organism
cloning of tyrosine decarboxylase gene dTdc1 Drosophila melanogaster
cloning of tyrosine decarboxylase gene dTdc2 Drosophila melanogaster

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Tyrosine Drosophila melanogaster flies with a mutation in dTdc2 lack neural tyramine and octopamine and are female sterile due to egg retention. Dtdc2 mutants release eggs into the oviducts but are unable to deposit them Tyramine + CO2
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Organism

Organism UniProt Comment Textmining
Drosophila melanogaster
-
dTdc1
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Drosophila melanogaster
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dTdc2
-

Source Tissue

Source Tissue Comment Organism Textmining
additional information dTdc1 is expressed nonneurally Drosophila melanogaster
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additional information dTdc2 is expressed neurally Drosophila melanogaster
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Tyrosine flies with a mutation in dTdc2 lack neural tyramine and octopamine and are female sterile due to egg retention. Dtdc2 mutants release eggs into the oviducts but are unable to deposit them Drosophila melanogaster Tyramine + CO2
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?

Synonyms

Synonyms Comment Organism
dTdc1
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Drosophila melanogaster
dTdc2
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Drosophila melanogaster
TDC
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Drosophila melanogaster