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Literature summary for 4.1.1.25 extracted from

  • El-Ahmady, S.H.; Nessler, C.L.
    Cellular localization of tyrosine decarboxylase expression in transgenic opium poppy and tobacco (2001), Plant Cell Rep., 20, 313-317.
No PubMed abstract available

Cloned(Commentary)

Cloned (Comment) Organism
expression of TyDC5 fused to beta-glucuronidase in Papaver somniferum and in Nicotiana tabacum Papaver somniferum

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Tyrosine Papaver somniferum first enzyme in poppy alkaloid biosynthesis, first biosynthetic step in the tetrahydroisoquinoline pathway, TyDC serves as a channel between the aromatic amino acids L-thyrosine and L-dopa and the biosynthesis of all of the opium poppy alkaloids Tyramine + CO2
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?

Organism

Organism UniProt Comment Textmining
Papaver somniferum
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opium poppy, TyDC gene family with about 15 members, TyDC5
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Source Tissue

Source Tissue Comment Organism Textmining
additional information recombinant TyDC5 expression pattern, not in poppy laticifers, about 15 members of the TyDC gene family show differences in developmental, tissue-specific and inducible gene expression Papaver somniferum
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root recombinant TyDC5, vascular cylinder surrounding the xylem Papaver somniferum
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shoot recombinant TyDC5, xylem parenchyma Papaver somniferum
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-Dopa
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Papaver somniferum dopamine + CO2
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?
L-Tyrosine very substrate-specific Papaver somniferum Tyramine + CO2
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?
L-Tyrosine first enzyme in poppy alkaloid biosynthesis, first biosynthetic step in the tetrahydroisoquinoline pathway, TyDC serves as a channel between the aromatic amino acids L-thyrosine and L-dopa and the biosynthesis of all of the opium poppy alkaloids Papaver somniferum Tyramine + CO2
-
?

Synonyms

Synonyms Comment Organism
TYDC
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Papaver somniferum