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Literature summary for 4.1.1.25 extracted from
- Plant tyrosine decarboxylase can be strongly inhibited by L-alpha-aminooxy-beta-phenylpropionate (1986), Planta, 167, 101-105.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| alpha-Fluoromethyl(3,4-dihydroxyphenyl)alanine | - |
Enterococcus faecalis |  |
| alpha-Fluoromethyl(3,4-dihydroxyphenyl)alanine | - |
Hordeum vulgare | |
| alpha-Fluoromethyltyrosine | - |
Enterococcus faecalis | |
| alpha-Fluoromethyltyrosine | - |
Hordeum vulgare | |
| alpha-Fluoromethyltyrosine | weak | Nicotiana tabacum | |
| alpha-Fluoromethyltyrosine | weak | Syringa vulgaris | |
| L-alpha-Aminooxy-beta-phenylpropionate | - |
Hordeum vulgare | |
| L-alpha-Aminooxy-beta-phenylpropionate | - |
Syringa vulgaris | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Tyr | Syringa vulgaris | possibly involved in the pathway of salidroside formation | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Enterococcus faecalis | - |
- |
- |
| Hordeum vulgare | - |
- |
- |
| Nicotiana tabacum | - |
- |
- |
| Sanguinaria canadensis | - |
- |
- |
| Syringa vulgaris | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| partial | Syringa vulgaris |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cell culture | - |
Syringa vulgaris | - |
| rhizome | - |
Sanguinaria canadensis | - |
| root | of 2-day-old seedlings | Hordeum vulgare | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-Tyr | - |
Hordeum vulgare | Tyramine + CO2 | - |
? | |
| L-Tyr | - |
Nicotiana tabacum | Tyramine + CO2 | - |
? | |
| L-Tyr | - |
Enterococcus faecalis | Tyramine + CO2 | - |
? | |
| L-Tyr | - |
Syringa vulgaris | Tyramine + CO2 | - |
? | |
| L-Tyr | - |
Sanguinaria canadensis | Tyramine + CO2 | - |
? | |
| L-Tyr | possibly involved in the pathway of salidroside formation | Syringa vulgaris | ? | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Enterococcus faecalis | |
| pyridoxal 5'-phosphate | functional group | Hordeum vulgare | |
| pyridoxal 5'-phosphate | functional group | Nicotiana tabacum | |
| pyridoxal 5'-phosphate | functional group | Syringa vulgaris | |
| pyridoxal 5'-phosphate | functional group | Sanguinaria canadensis | |
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Release 2023.1 (January 2023)
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