Cloned (Comment) | Organism |
---|---|
gene hdc, cDNA is cloned from chicken hypothalamic mRNA, sequence comparisons, quantitative real-time PCR enzyme expression analysis, DNA and amino acid sequence determination and anlysis, recombinant expression, the expressed protein shows high enzymatic activity | Gallus gallus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | Gallus gallus | - |
histamine + CO2 | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Gallus gallus | A0A068Q816 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | in the tuberomammillary nucleus of the posterior hypothalamus | Gallus gallus | - |
hypothalamus | highly expressed in the hypothalamic infundibulum, the cells containing HDC mRNA are localized in the medial mammillary nucleus of the hypothalamic infundibulum | Gallus gallus | - |
neuron | histaminergic | Gallus gallus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-histidine | - |
Gallus gallus | histamine + CO2 | - |
? |
Synonyms | Comment | Organism |
---|---|---|
HDC | - |
Gallus gallus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Gallus gallus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.4 | - |
assay at | Gallus gallus |
General Information | Comment | Organism |
---|---|---|
physiological function | neuronal histamine exerts anorexigenic effects in chicks | Gallus gallus |