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Literature summary for 4.1.1.20 extracted from

  • Weyand, S.; Kefala, G.; Svergun, D.I.; Weiss, M.S.
    The three-dimensional structure of diaminopimelate decarboxylase from Mycobacterium tuberculosis reveals a tetrameric enzyme organisation (2009), J. Struct. Funct. Genomics, 10, 209-217.
    View publication on PubMed
Search for more literature for 4.1.1.20

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Mycobacterium tuberculosis

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging drop vapor diffusion method, using 20-23% (w/v) PEG-MME 5000, 0.1 M MES pH 6.1-6.6, and 60 mM (NH4)2SO4 Mycobacterium tuberculosis

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
189000
-
 X-ray scattering Mycobacterium tuberculosis

Organism

Organism UniProt Comment Textmining
Mycobacterium tuberculosis P9WIU7
-
-
Mycobacterium tuberculosis H37Rv P9WIU7
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Mycobacterium tuberculosis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
meso-2,6-Diaminoheptanedioate
-
 Mycobacterium tuberculosis L-Lysine + CO2
-
 ?
meso-2,6-Diaminoheptanedioate
-
 Mycobacterium tuberculosis H37Rv L-Lysine + CO2
-
 ?

Subunits

Subunits Comment Organism
homodimer DAPDC is predominantly dimeric in solution Mycobacterium tuberculosis
homotetramer an equilibrium may exist between the dimeric and the tetrameric form, X-ray crystallography Mycobacterium tuberculosis

Synonyms

Synonyms Comment Organism
DAPDC
-
 Mycobacterium tuberculosis

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Mycobacterium tuberculosis