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Literature summary for 4.1.1.20 extracted from

  • Momany, C.; Levdikov, V.; Blagova, L.; Crews, K.
    Crystallization of diaminopimelate decarboxylase from Escherichia coli, a stereospecific D-amino-acid decarboxylase (2002), Acta Crystallogr. Sect. D, 58, 549-552.
    View publication on PubMed
Search for more literature for 4.1.1.20

Cloned(Commentary)

Cloned (Comment) Organism
overexpression in Escherichia coli Escherichia coli

Crystallization (Commentary)

Crystallization (Comment) Organism
vapor-diffusion at room temperature, crystals are grown from 0.002 mL DDC solution in 50 mM sodium MES, pH 6.0 and 0.1 mM pyridoxal 5'-phosphate mixed with 0.002 ml well solution consisting of 1.44-1.54 M lithium sulfate, 50 mM MES, pH 6.0, and 0.1 mM pyridoxal 5'-phosphate Escherichia coli

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
52500
-
 gel filtration, recombinant DDC Escherichia coli
200000
-
 ultracentrifugation Escherichia coli

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
meso-2,6-Diaminoheptanedioate Escherichia coli final step in L-lysine biosynthesis L-Lysine + CO2
-
 ?

Organism

Organism UniProt Comment Textmining
Escherichia coli
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
7
-
 recombinant DDC, 37°C Escherichia coli
9
-
 native DDC Escherichia coli

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
meso-2,6-Diaminoheptanedioate
-
 Escherichia coli L-Lysine + CO2
-
 ?
meso-2,6-Diaminoheptanedioate final step in L-lysine biosynthesis Escherichia coli L-Lysine + CO2
-
 ?

Synonyms

Synonyms Comment Organism
DDC
-
 Escherichia coli

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
 Escherichia coli