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Literature summary for 4.1.1.20 extracted from
- Purification and properties of meso-alpha,epsilon-diaminopimelate decarboxylase from Bacillus sphaericus (1981), Agric. Biol. Chem., 45, 1513-1514.
No PubMed abstract available
Activating Compound
| Activating Compound | Comment | Organism | Structure |
|---|---|---|---|
| 2,3-Dimercaptopropan-1-ol | activates | Lysinibacillus sphaericus |  |
| dithiothreitol | activates | Lysinibacillus sphaericus | |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| D,L-alpha-aminoheptanedioate | - |
Lysinibacillus sphaericus | |
| L-2,4-diaminobutyrate | - |
Lysinibacillus sphaericus | |
| L-cystine | - |
Lysinibacillus sphaericus | |
| L-lysine | - |
Lysinibacillus sphaericus | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.7 | - |
meso-2,6-diamininoheptanedioate | - |
Lysinibacillus sphaericus | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 80000 | - |
gel filtration | Lysinibacillus sphaericus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| meso-2,6-Diaminoheptanedioate | Lysinibacillus sphaericus | lysine biosynthesis | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Lysinibacillus sphaericus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Lysinibacillus sphaericus |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 28.3 | - |
- |
Lysinibacillus sphaericus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| Lanthionine | slowly | Lysinibacillus sphaericus | ? | - |
? | |
| meso-2,6-Diaminoheptanedioate | - |
Lysinibacillus sphaericus | L-Lysine + CO2 | - |
? | |
| meso-2,6-Diaminoheptanedioate | lysine biosynthesis | Lysinibacillus sphaericus | ? | - |
? | |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
enzyme assay at | Lysinibacillus sphaericus |
Temperature Stability [°C]
| Temperature Stability Minimum [°C] | Temperature Stability Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 50 | - |
stable for 10 min at pH 6.0-7.5 | Lysinibacillus sphaericus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 6.8 | 7.9 | - |
Lysinibacillus sphaericus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | Km: 0.0061 mM | Lysinibacillus sphaericus | |
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