Literature summary for 4.1.1.2 extracted from

Chakraborty, N.; Ghosh, R.; Ghosh, S.; Narula, K.; Tayal, R.; Datta, A.; Chakraborty, S.
Reduction of oxalate levels in tomato fruit and consequent metabolic remodeling following overexpression of a fungal oxalate decarboxylase (2013), Plant Physiol., 162, 364-378.

Cloned(Commentary)

Cloned (Comment)	Organism
gene FvOXDC, recombinant expression in Solanum lycopersicum fruits under the control of a fruit-specific promoter E8.2 being active upon ethylene induction only in ripening fruits, via Agrobacterium tumefaciens-mediated transformation, OXDC is targeted to the cell vacuole in the transgenic fruits. The transgenic fruits show up to a 90% reduction in oxalate content, which correlates with concomitant increases in calcium, iron, and citrate, compared to wild-type fruits. Expression of OXDC affects neither CO2 assimilation rates nor results in any detectable morphological differences in the transgenic plants. OXDC-responsive proteins involved in metabolism and stress responses represent the most substantially up- and down-regulated categories, respectively, in the transgenic fruit, compared with those of wild-type plants, proteome analysis, overview	Flammulina velutipes

Cloned (Comment)

Organism

gene FvOXDC, recombinant expression in Solanum lycopersicum fruits under the control of a fruit-specific promoter E8.2 being active upon ethylene induction only in ripening fruits, via Agrobacterium tumefaciens-mediated transformation, OXDC is targeted to the cell vacuole in the transgenic fruits. The transgenic fruits show up to a 90% reduction in oxalate content, which correlates with concomitant increases in calcium, iron, and citrate, compared to wild-type fruits. Expression of OXDC affects neither CO2 assimilation rates nor results in any detectable morphological differences in the transgenic plants. OXDC-responsive proteins involved in metabolism and stress responses represent the most substantially up- and down-regulated categories, respectively, in the transgenic fruit, compared with those of wild-type plants, proteome analysis, overview

Flammulina velutipes

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
oxalate + H+	Flammulina velutipes	-	formate + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Flammulina velutipes	-	-	-
no activity in Solanum lycopersicum	-	in fruits	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
oxalate + H+	-	Flammulina velutipes	formate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
FvOXDC	-	Flammulina velutipes
OXDC	-	Flammulina velutipes

General Information

General Information	Comment	Organism
evolution	oxalate decarboxylase belongs to the low-pH-inducible cupin superfamily of enzymes	Flammulina velutipes