Literature summary for 4.1.1.2 extracted from

Grujic, D.; Salido, E.C.; Shenoy, B.C.; Langman, C.B.; McGrath, M.E.; Patel, R.J.; Rashid, A.; Mandapati, S.; Jung, C.W.; Margolin, A.L.
Hyperoxaluria is reduced and nephrocalcinosis prevented with an oxalate-degrading enzyme in mice with hyperoxaluria (2009), Am. J. Nephrol., 29, 86-93.

Search for more literature for 4.1.1.2

Application

Application	Comment	Organism
medicine	OxDc-CLEC reduces hyperoxaluria and ameliorates nephrocalcinosis and urolithiasis	Mus musculus

General Stability

General Stability	Organism
crystallization of OxDc noticeably increases the enzyme's specific activity and broadenes its pH-activity profile at both acidic pH 3.0 and neutral pH 7.0	Mus musculus

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
oxalate + H+	-	Mus musculus	formate + CO2	-	?

Synonyms

Synonyms	Comment	Organism
oxalate-decarboxylase	-	Mus musculus
OxDc-CLEC	commercial preparation	Mus musculus

Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.

Release 2023.1 (January 2023)