Literature summary for 4.1.1.19 extracted from

Kierszenbaum, F.; Wirth, J.J.; McCann, P.P.; Sjoerdsma, A.
Arginine decarboxylase inhibitors reduce the capacity of Trypanosoma cruzi to infect and multiply in mammalian host cells (1987), Proc. Natl. Acad. Sci. USA, 84, 4278-4282.

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Inhibitors

Inhibitors	Comment	Organism	Structure
(E)-alpha-Monofluoromethyl-3-4-dehydroarginine	irreversible inhibitor may have a potential application in chemotherapy against Trypanosoma cruzi infection	Trypanosoma cruzi
DL-alpha-difluoromethylarginine	irreversible inhibitor may have a potential application in chemotherapy against Trypanosoma cruzi infection	Trypanosoma cruzi
Monofluoromethylagmatine	irreversible inhibitor may have a potential application in chemotherapy against Trypanosoma cruzi infection	Trypanosoma cruzi

Organism

Organism	UniProt	Comment	Textmining
Trypanosoma cruzi	-	-	-

Source Tissue

Source Tissue	Comment	Organism	Textmining

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-arginine	-	Trypanosoma cruzi	agmatine + CO2	-	?

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Release 2023.1 (January 2023)