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Literature summary for 4.1.1.18 extracted from

  • Yamamoto, S.; Imamura, T.; Kusaba, K.; Shinoda, S.
    Purification and some properties of inducible lysine decarboxylase from Vibrio parahaemolyticus (1991), Chem. Pharm. Bull., 39, 3067-3070.
    View publication on PubMed
Search for more literature for 4.1.1.18

General Stability

General Stability Organism
dithiothreitol is required for stabilization during purification and storage Vibrio parahaemolyticus
pyridoxal 5'-phosphate is indispensable for stability Vibrio parahaemolyticus

Inhibitors

Inhibitors Comment Organism Structure
6-aminohexanoate
-
 Vibrio parahaemolyticus
alpha-Difluoromethylcadaverine
-
 Vibrio parahaemolyticus
alpha-Monofluoromethylcadaverine
-
 Vibrio parahaemolyticus
alpha-Trifluoromethylcadaverine
-
 Vibrio parahaemolyticus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
3.2
-
 L-Lys
-
 Vibrio parahaemolyticus

Molecular Weight [Da]

Molecular Weight [Da] Molecular Weight Maximum [Da] Comment Organism
79000
-
 7 * 79000, SDS-PAGE Vibrio parahaemolyticus
531000
-
 gel filtration Vibrio parahaemolyticus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-Lys Vibrio parahaemolyticus inducible enzyme ?
-
 ?
L-Lys Vibrio parahaemolyticus AQ 3627 inducible enzyme ?
-
 ?

Organism

Organism UniProt Comment Textmining
Vibrio parahaemolyticus
-
-
-
Vibrio parahaemolyticus AQ 3627
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Vibrio parahaemolyticus

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
additional information
-
-
 Vibrio parahaemolyticus

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
delta-Hydroxylysine 17% of the activity with L-Lys Vibrio parahaemolyticus 1,5-Diamino-2-hydroxypentane + CO2
-
 ?
delta-Hydroxylysine 17% of the activity with L-Lys Vibrio parahaemolyticus AQ 3627 1,5-Diamino-2-hydroxypentane + CO2
-
 ?
L-Lys
-
 Vibrio parahaemolyticus Cadaverine + CO2
-
 ?
L-Lys
-
 Vibrio parahaemolyticus AQ 3627 Cadaverine + CO2
-
 ?
L-Lys inducible enzyme Vibrio parahaemolyticus ?
-
 ?
L-Lys inducible enzyme Vibrio parahaemolyticus AQ 3627 ?
-
 ?
S-Aminoethyl-L-Cys 23% of the activity with L-Lys Vibrio parahaemolyticus 1-Amino-2-(S-aminoethyl)mercaptoethane + CO2
-
 ?
S-Aminoethyl-L-Cys 23% of the activity with L-Lys Vibrio parahaemolyticus AQ 3627 1-Amino-2-(S-aminoethyl)mercaptoethane + CO2
-
 ?

Subunits

Subunits Comment Organism
heptamer 7 * 79000, SDS-PAGE Vibrio parahaemolyticus

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
45 50
-
 Vibrio parahaemolyticus

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
20 80 20°C: about 25% of maximal activity, 80°C: about 95% of maximal activity Vibrio parahaemolyticus

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
80
-
 pH 5.5, 10 min, 35% loss of activity Vibrio parahaemolyticus

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5.5
-
-
 Vibrio parahaemolyticus

pH Range

pH Minimum pH Maximum Comment Organism
4.5 7 pH 4.5: about 35% of maximal activity, pH 7.0: about 60% of maximal activity Vibrio parahaemolyticus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate required as cofactor Vibrio parahaemolyticus