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Literature summary for 4.1.1.17 extracted from

  • Fogle, E.J.; Toney, M.D.
    Analysis of catalytic determinants of diaminopimelate and ornithine decarboxylases using alternate substrates (2011), Biochim. Biophys. Acta, 1814, 1113-1119.
    View publication on PubMedView publication on EuropePMC

Inhibitors

Inhibitors Comment Organism Structure
D-ornithine
-
Saccharomyces cerevisiae
putrescine product inhibition Saccharomyces cerevisiae

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.122
-
L-ornithine CO2 assay, pH 7.8, 25°C Saccharomyces cerevisiae
0.214
-
L-ornithine circular dichroism assay, pH 7.8, 25°C Saccharomyces cerevisiae

Organism

Organism UniProt Comment Textmining
Saccharomyces cerevisiae
-
-
-
Saccharomyces cerevisiae WDHT668
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
Saccharomyces cerevisiae putrescine + CO2
-
?
L-ornithine
-
Saccharomyces cerevisiae WDHT668 putrescine + CO2
-
?

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
3.3
-
L-ornithine CO2 assay, pH 7.8, 25°C Saccharomyces cerevisiae
4.2
-
L-ornithine circular dichroism assay, pH 7.8, 25°C Saccharomyces cerevisiae

Ki Value [mM]

Ki Value [mM] Ki Value maximum [mM] Inhibitor Comment Organism Structure
0.25
-
putrescine pH 7.8, 25°C Saccharomyces cerevisiae
0.38
-
D-ornithine pH 7.8, 25°C Saccharomyces cerevisiae

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
20
-
L-ornithine circular dichroism assay, pH 7.8, 25°C Saccharomyces cerevisiae
27
-
L-ornithine CO2 assay, pH 7.8, 25°C Saccharomyces cerevisiae