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Literature summary for 4.1.1.17 extracted from

  • Maekitie, L.T.; Kanerva, K.; Andersson, L.C.
    Ornithine decarboxylase regulates the activity and localization of rhoA via polyamination (2009), Exp. Cell Res., 315, 1008-1014.
    View publication on PubMed

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-ornithine Rattus norvegicus
-
putrescine + CO2
-
?

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-ornithine
-
Rattus norvegicus putrescine + CO2
-
?

Synonyms

Synonyms Comment Organism
ODC
-
Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
pyridoxal 5'-phosphate
-
Rattus norvegicus

Expression

Organism Comment Expression
Rattus norvegicus no decrease in the ODC activity is detected after treatment with 0.2 mM monodansylcadaverine or cystamine additional information
Rattus norvegicus cancerous cells display constitutively elevated ODC activity up

General Information

General Information Comment Organism
physiological function ornithine decarboxylase regulates the activity and localization of rhoA via polyamination, ODC activity is needed for the maintenance of rhoA at the plasma membrane Rattus norvegicus