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Literature summary for 4.1.1.17 extracted from

  • Tang, H.; Ariki, K.; Ohkido, M.; Murakami, Y.; Matsufuji, S.; Li, Z.; Yamamura, K.
    Role of ornithine decarboxylase antizyme inhibitor in vivo (2009), Genes Cells, 14, 79-87.
    View publication on PubMed

Protein Variants

Protein Variants Comment Organism
additional information establishment of an embryonic stem cell clone with disrupted Azin1 gene by the gene trap technique, construction of a mutant mouse line using these trapped embryonic stem cells. Homozygous mutant mice die at P0 with abnormal liver morphology, deletion of Azin1 in homozygous mice results in the degradation of ODC, and reduced the biosynthesis of putrescine and spermidine, genotype and phenotype, overview Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
antizyme role of ornithine decarboxylase antizyme inhibitor in vivo, ODC antizyme inhibitor, AZI, regulates ODC activity in cell cultures Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
additional information Mus musculus role of ornithine decarboxylase antizyme inhibitor in vivo, ODC antizyme inhibitor, AZI, plays an important role in regulating the levels of ODC, putrescine and spermidine in mice, and is essential for the survival of mice, overview ?
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Organism

Organism UniProt Comment Textmining
Mus musculus
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information role of ornithine decarboxylase antizyme inhibitor in vivo, ODC antizyme inhibitor, AZI, plays an important role in regulating the levels of ODC, putrescine and spermidine in mice, and is essential for the survival of mice, overview Mus musculus ?
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?

Synonyms

Synonyms Comment Organism
ODC
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Mus musculus