Protein Variants | Comment | Organism |
---|---|---|
additional information | establishment of an embryonic stem cell clone with disrupted Azin1 gene by the gene trap technique, construction of a mutant mouse line using these trapped embryonic stem cells. Homozygous mutant mice die at P0 with abnormal liver morphology, deletion of Azin1 in homozygous mice results in the degradation of ODC, and reduced the biosynthesis of putrescine and spermidine, genotype and phenotype, overview | Mus musculus |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
antizyme | role of ornithine decarboxylase antizyme inhibitor in vivo, ODC antizyme inhibitor, AZI, regulates ODC activity in cell cultures | Mus musculus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | Mus musculus | role of ornithine decarboxylase antizyme inhibitor in vivo, ODC antizyme inhibitor, AZI, plays an important role in regulating the levels of ODC, putrescine and spermidine in mice, and is essential for the survival of mice, overview | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
additional information | role of ornithine decarboxylase antizyme inhibitor in vivo, ODC antizyme inhibitor, AZI, plays an important role in regulating the levels of ODC, putrescine and spermidine in mice, and is essential for the survival of mice, overview | Mus musculus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ODC | - |
Mus musculus |