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Literature summary for 4.1.1.17 extracted from
- Ornithine decarboxylase activity is affected in primary astrocytes but not in secondary cell lines exposed to 872 MHz RF radiation (2007), Int. J. Radiat. Biol., 83, 367-374.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | serum deprivation reduces enzyme activity by 87.6% in SH-SY5Y cells, overview, enzyme activity is not affected in secondary cell lines exposed to 872 MHz RF radiation, overview | Homo sapiens | |
| additional information | enzyme activity is not affected in secondary cell lines exposed to 872 MHz RF radiation, overview | Mus musculus | |
| additional information | serum deprivation reduces enzyme activity by 97.2% and by 87.0% in C6 cells, overview, enzyme activity is affected in primary astrocytes but not in secondary cell lines exposed to 872 MHz RF radiation, overview | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-ornithine | Mus musculus | - |
putrescine + CO2 | - |
? |  |
| L-ornithine | Homo sapiens | - |
putrescine + CO2 | - |
? | |
| L-ornithine | Rattus norvegicus | - |
putrescine + CO2 | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
| Mus musculus | - |
- |
- |
| Rattus norvegicus | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| astrocyte | primary cells | Rattus norvegicus | - |
| brain | - |
Rattus norvegicus | - |
| C6 glioma cell | - |
Rattus norvegicus | - |
| fibroblast | - |
Mus musculus | - |
| glioblastoma cell | - |
Rattus norvegicus | - |
| L-929 cell | - |
Mus musculus | - |
| neuroblastoma cell | - |
Homo sapiens | - |
| SH-SY5Y cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-ornithine | - |
Mus musculus | putrescine + CO2 | - |
? | |
| L-ornithine | - |
Homo sapiens | putrescine + CO2 | - |
? | |
| L-ornithine | - |
Rattus norvegicus | putrescine + CO2 | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| ODC | - |
Mus musculus |
| ODC | - |
Homo sapiens |
| ODC | - |
Rattus norvegicus |
Temperature Optimum [°C]
| Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
|---|---|---|---|
| 37 | - |
assay at | Mus musculus |
| 37 | - |
assay at | Homo sapiens |
| 37 | - |
assay at | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
assay at | Mus musculus |
| 7.4 | - |
assay at | Homo sapiens |
| 7.4 | - |
assay at | Rattus norvegicus |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyridoxal 5'-phosphate | - |
Mus musculus | |
| pyridoxal 5'-phosphate | - |
Homo sapiens | |
| pyridoxal 5'-phosphate | - |
Rattus norvegicus | |
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Release 2023.1 (January 2023)
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