Literature summary for 4.1.1.17 extracted from

Kern, A.D.; Oliveira, M.A.; Coffino, P.; Hackert, M.L.
Structure of mammalian ornithine decarboxylase at 1.6 A resolution: stereochemical implications of PLP-dependent amino acid decarboxylases (1999), Structure Fold. Des., 7, 567-581.

Crystallization (Commentary)

Crystallization (Comment)	Organism
crystals of truncated ODC at 1.6 A resolution, 0.01 mM of silica hydrogel on a microbridge, sitting within a 3.25 ml well containing 1 ml 10% polyethylene glycol is gently covered with 0.01 ml 26% polyethylene glycol 3350, the microbridge is transferred to a well containing 1 ml 26% polyethylene glycol 3350, protein solution containing 12 mg/ml ODC, 2.5 mM dithiothreitol, 1 mM EDTA is added to the microbridge and the well is sealed with tape, plate is left undisturbed in the dark at room temperature for 2 weeks	Mus musculus

Crystallization (Comment)

Organism

crystals of truncated ODC at 1.6 A resolution, 0.01 mM of silica hydrogel on a microbridge, sitting within a 3.25 ml well containing 1 ml 10% polyethylene glycol is gently covered with 0.01 ml 26% polyethylene glycol 3350, the microbridge is transferred to a well containing 1 ml 26% polyethylene glycol 3350, protein solution containing 12 mg/ml ODC, 2.5 mM dithiothreitol, 1 mM EDTA is added to the microbridge and the well is sealed with tape, plate is left undisturbed in the dark at room temperature for 2 weeks

Mus musculus

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
L-ornithine	Mus musculus	first step in polyamine biosynthesis	putrescine + CO2	-	?

Organism

Organism	UniProt	Comment	Textmining
Mus musculus	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
L-ornithine	-	Mus musculus	putrescine + CO2	-	?
L-ornithine	first step in polyamine biosynthesis	Mus musculus	putrescine + CO2	-	?

Synonyms

Synonyms	Comment	Organism
ODC	-	Mus musculus

Cofactor

Cofactor	Comment	Organism	Structure
pyridoxal 5'-phosphate	-	Mus musculus

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Release 2023.1 (January 2023)